(Les étudiants supervisés sont soulignés)

  1. Villandré, L., Labbe, A., Brenner, B., Roger, M. and Stephens, D. (2019). Transmission clusters in the HIV-1 epidemic among men who have sex with men in Montreal, Quebec, Canada. To appear in  PLos One.
  2. Stipancic, J., Saunier, N., Labbe, A. and Miranda-Moreno L. (2019). Network Screening for Large Urban Road Networks: Using GPS Data and Surrogate Measures to Model Crash Frequency and Severity. To appear in Accident Analysis and Prevention
  3. Jacques, C., Courchesne, V., Meilleur-Simard, A.A., Mineau, S., Ferguson, S., Cousineau, D., Labbe, A., Mottron, and L., Dawson, M. (2019) What interests young autistic children? Assessing repetitive behaviors and object explorations in a stimulating play situation. PLos One, 13(12), 1-7.
  4. Steiger, H., Booij, L., Kahan, E.,  McGregor, K., Thaler, L., Fletcher, E., Labbe, A., Joober, R., Israël, M., Szyf, M., Agellon, L., Gauvin, L, St-Hilaire, A. and Rossi, E.  (2019). A longitudinal, epigenomewide study of DNA methylation in Anorexia Nervosa: Results in actively ill, partially weight restored, long-term remitted, and non-eating-disordered women. Journal of Psychiatry and Neuroscience, 44(2), 1-9.
  5. Shokoohi, F., Stephens, D., Bourque, G., Pastinen, T., Greenwood, C., Labbe, A. (2019). A Novel Profiling Method for Identifying Differentially Methylated Sites in Bisulfite Sequencing Data. To appear in Biometrics.
  6. Stipancic, J., Miranda-Moreno, L., Saunier, N. and Labbe, A. (2018). Surrogate Safety and Network Screening: Modelling Crash Frequency Using GPS Travel Data and Latent Gaussian Spatial Models. Accident Analysis and Prevention, 120:174-187.
  7. Fageera, W., Sengupta, S., Labbe, A., Grizenko, N. and Joober, R. (2018). DRD3 gene and ADHD: a pharmacy-behavioural genetic study. NeuroMolecular Medicine, 20(4):515-524.
  8. Sengupta, S. et al. (2018). Dissecting genetic crosstalk between ADHD and other neurodevelopmental disorders: evidence from behavioural, pharmacological and brain imaging investigations. Psychiatry Research, 269:652-657.
  9. Villandré, L., Labbe, A., Brenner, B.G., Roger, M. and Stephens, D.A. (2018). DM-PhyClus: A Bayesian phylogenetic algorithm for infectious disease transmission cluster inference. BMC Bioinformatics, 19:324.
  10. Benedet, A.B., Yu, L., Labbe, A., Mathotaarachchi, S., Pascoal, T., Shin, M., Kang, M.S., Gauthier, S., Rouleau, G.A., Poirier, J., Bennett, D.A. and Rosa-Neto, P. (2018). CYP2C19 variant mitigates Alzheimer’s disease pathophysiology in vivo and post mortem. Neurology: Genetics, 4(1):e216.
  11. Huguet, G., Schramm, C., Douard, E., Jiang, L., Labbe, A., Lemyre, E., Poline, J.B., Loth, E., Toro, R., Schumann, G.,  Conrod, P.,  Pausova, Z., Greenwood, C., Paus, T., Bourgeron, T., Jacquemont, S and the IMAGEN Consortium,. (2018). Measuring and predicting the effect of copy-number variants on general intelligence in unselected populations. Journal of the American Medical Association, 75(5):447-457.
  12. Turgeon, M., Oualkacha, K., Ciampi, A., Miftah, H., Dehghan, G., Zanke, B.W., Benedet, A.L., Rosa-Neto, P., Greenwood, C.M.T., Labbe, A., for the Alzheimer’s Disease Neuroimaging Initiative. (2018). Principal component of explained variance: an efficient and optimal data dimension reduction framework for association studies. Statistical methods in medical research, 27(5), 1331-1350.
  13. Pana, R., Labbe, A., Dubeau, F. (2018). Evaluation of the “non-epileptic” patient in a tertiary center epilepsy clinic.Epilepsy and Behavior, 79:100-105.
  14. Fageera, W.,Traicu, A., Sengupta, S., Fortier, M.E., Grizenko, N., Choudhry, Z., Labbe, A. and Joober, R. (2018). Placebo response and its determinants in children with ADHD across multiple observers and settings: a randomized clinical trial. International Journal of Methods in Psychiatric Research, 27(1). doi: 10.1002/mpr.
  15. Stipancic, J., Miranda-Moreno, L., Labbe, A., and Saunier, N. (2017). Measuring and visualizing spacetime congestion patterns in an urban road network using large scale smartphone collected GPS data. Transportation Letters: the International Journal of Transportation Research. 1-11. 10.1080/19427867.2017.1374022.
  16. Huang, O., Infante-Rivard, C. and Labbe, A. (2017). Analysis of case-parent trios for imprinting effect using a loglinear model with adjustment for sex-of-parent-specific transmission ratio distortion. Human Genetics, 138(8), 951-961.
  17. Forest, M., Itturia-Medina, Y., Goldman, J., Kleinman, C., Lovato, A., Oros Klein, K., Evans, A., Ciampi, A, Labbe, A. and Greenwood, C. (2017) Gene networks show associations with seed region connectivity. Human Brain Mapping, 38(6), 3126–3140.
  18. Romancyshyn, T., Miranda-Moreno, L. and Labbe A. (2017), The effect of weather on arterial travel speeds from Bluetooth sensor data using a mixed regression approach. To appear in Transportmetrica.
  19. Pascoala, T., Mathotaarachchia, S., Shin, M., Benedet A., Mohades, S., Wanga, S., Beaudry, T., Kang, M.S., Soucy, J.P., Labbe, A., Gauthier, S. and Rosa-Neto, P. for the Alzheimer’s disease Neuroimaging Initiative. (2017) Synergistic interaction between amyloid and tau predicts the progression to dementia. Alzheimer’s and Dementia, 13(6), 644-653.
  20. Cunningham, E., Ciampi, A., Joober, J. and Labbe, A. (2017) Estimating and correcting optimism bias in multivariate PLS regression: application to the study of the association between Single Nucleotide Polymorphisms (SNPs) and multivariate traits in Attention Deficit Hyperactivity Disorder (ADHD). Proceedings from PLS2014, Springer, 103-113.
  21. McGregor, K., Labbe, A. and Greenwood, C. (2017) Response to Correcting for celltype effects in DNA methylation studies: Reference-based method outperforms latent variable approaches in empirical studies. Genome Biology, 18:25.
  22. Pascoal, T., Mathotaarachchi, S., Mohades, S., Benedet, A., Chung, C., Shin, M., Wang, S., Beaudry, T., Su Kang, M., Soucy, J.P., Labbe, A., Gauthier, S. and Rosa-Neto, P. (2017). Amyloid-beta and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer’s disease. Molecular Psychiatry, 22(2), 306-311.
  23. Bhatnagar S., Greenwood C., Labbe A. (2016) Assessing transmission ratio distortion in extended families: a comparison of analysis methods. BMC Proceedings, v.10(Suppl 7).
  24. Huang, O, Infante-Rivard, C. and Labbe, A. (2016). Analysis of Case-Parent Trios Using a Loglinear Model with Adjustment for Transmission Ratio Distortion. Frontiers in Genetics, 7, p155.
  25. Mathotaarachchi, S., Wang, S., Shin, M., Pascoal, T.A., Benedet, A.L., Su Kang, M., Beaudry, T., Fonov, V., Gauthier, S., Labbe, A. and Rosa-Neto, P. (2016). VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis. Frontiers in Neuroinformatics, 10:20.
  26. McGregor K., Bernatsky S., Colmegna I., Hudson M., Pastinen T., Labbe A.  and Greenwood C. (2016). An evaluation of methods correcting for cell type heterogeneity in DNA methylation studies. Genome Biology, 17:84.
  27. Steiger, H., Thaler, L., Gauvin, L., Joober, R., Labbe, A., Israel, M. and Kucer, A. (2016). Epistatic interactions involving DRD2, DRD4, and COMT polymorphisms and risk of substance abuse in women with binge-purge eating disturbances. Journal of Psychiatric Research, 77:8-14.
  28. Villandre, L., Stephens, D., Labbe, A. Gunthard, H., Kouyos, R. and Stadler, T. (2016). Assessment of Overlap of Phylogenetic Transmission Cluster and Communities in Simple Sexual Contact Networks: Application to HIV-1. PLos One, 11(2): e0148459.
  29. Klein K., Grinek S., Bernatsky, S., Bouchard, L., Ciampi, A., Colmegna, I., Fortin, Gao L., J.P., Hivert, M.F., Hudson, M., Kobor, M., Labbe A., MacIsaac, J., Meaney, M., Morin, A., O’Donnell, K., Pastinen, T., Van ljzendoorn, H.V., Voisin, G. and Greenwood C. (2016). Fun- tooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types. Bioinformatics, 32(4):593-5.
  30. Ducharme, S., Albaugh, M., Nguyen, T.V., Hudziak, J., Matéos Perez, J.M., Labbe, A., Evans, A.C. and  Karama, S. (2016) Trajectories of cortical thickness maturation in normal brain development  – The importance of quality control procedures. NeuroImage, 125:267-79.
  31. DuBois, J., Rousset, O., Rowley, J., Porras-Betancourt, M., Reader, A., Labbe, A., Massarweh, G., Soucy, JP, Rosa-Neto, P. and Kobayashi, E. (2016) Characterization of age/sex and the regional distribution of mGluR5 availability in the healthy human brain measured by high-resolution [(11)C]ABP688 PET. European Journal of Nuclear Medicine and Molecular Imaging, 43(1):152-62.
  32. Lessa Benedet, A., Labbe, A., Lemay, P., Zimmer, R., Pascoal, T., Leuzy, A., Mathotaarachchi, S., Mohades, S., Shin, M., Dionne-Laporte, A., Beaudry, T., Picard, C., Gauthier, S., Poirier, J., Rouleau, G. and Rosa-Neto, P. (2015). Epistasis analysis links immune cascades and cerebral amyloidosis. Journal of Neuroinflammation, 1;12:227.
  33. Ducharme, S., Albaugh, M., Nguyen, T.V., Hudziak, J., Matéos Perez, J.M., Labbe, A., Evans, A.C. and  Karama, S. (2015) Trajectories of cortical surface area and cortical volume maturation in normal brain development. Data in Brief, 5, 929-38.
  34. Lutz, PE, Zhou, Y., Labbe, A., Mechawar, N. and Turecki, G. (2015). Decreased Expression of Nociceptin/Orphanin FQ in the dorsal Anterior Cingulate Cortex of Suicides. European Neuropsychopharmacology, 25(11), 2008–2014.
  35. Romdhani, H., Hwang, H., Paradis, G., Roy-Gagnon, M.H. and Labbe, A. (2015). Pathway-based Association Study of Multiple Candidate Genes and Multiple Traits Using Structural Equation Models. Genetic Epidemiology, 39(2),101-113.
  36. O’Loughlin, J., Sylvestre, M.P., Labbe, A., Low, N., Roy-Gagnon, M.H., Dugas, E., Engert, J. and Karp, I. (2014) Genetic variants and early smoking and nicotine dependence in Canadian adolescents. PLoS ONE, 9(12): e115716.
  37. Fortin, J.P., Labbe, A., Lemire, M., Zanke, B., Hudson, T., Fertig, E., Greenwood, C., Hansen, K. (2014) Functional normalization of 450k methylation array data improves replication in large cancer studies. Genome Biology, 15:503.
  38. OLoughlin, J., Dugas, E., Brunet, J, … , Labbe, A., … , van Hulst, A. (2014) Cohort Profile: The Nicotine Dependence in Teens (NDIT) Study. International Journal of Epidemiology, 44(5), 1537-46.
  39. Pedneault, M., Labbe, A., Roy-Gagnon, M.H., Low, N., Dugas, E., Engert, J. and O’Loughlin, J. (2014). The association between CHRN genetic variants and dizziness at first inhalation of cigarette smoke. Addictive Behavior, 39(1), 316-320.
  40. Gauthier, S., Jia, J., Belleville, S., Doudet, D., Hsiung, G.Y., Labbe, A., Li, D., Qin, W., Rosa-Neto, P., Sadovnick, D., Soucy, J.P. and Wu, L. (2013). Canada-China Cohort Study of early-onset familial Alzheimer’s disease. Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association, 9 (4), P204.
  41. Imholte, G.C., Scott-Boyer, M.P., Labbe, A., Deschepper, C. and Gottardo, R. (2013) iBMQ: a R/Bioconductor package for integrated Bayesian modeling of eQTL data. Bioinformatics, 29(21), 2797-2798.
  42. Low, N. C., O’Loughlin, J., Labbe, A., Roy-Gagnon, M. H., Dugas, E., and Engert, J. C. (2013). Genetic determinants vary across early cigarette smoking and nicotine dependence phenotypes in adolescents. Biological Psychiatry, 73(9), 289S.
  43. Ciampi, A., Yang, L., Labbe, A. and Merette, C. (2013) PLS Regression and Hybrid Methods in Genomics Association Studies. New Perspectives in Partial Least Squares and Related Methods – Springer Proceedings in Mathematics \& Statistics, 56, 107-116.
  44. Malard, L., Kakinami, L., OLoughlin, J., Roy-Gagnon, M.H., Labbe, A., Pilote, L., Hamet, P., Tremblay, J. and Paradis, G. (2013) The association between the angiotensin-converting enzyme-2 (ACE2) gene and blood pressure in a cohort study of adolescents. BMC Medical Genetics, 5, 14:117.
  45. Labbe, A., Huang, O. and Infante-Rivard, C. (2013) Transmission ratio distortion: a neglected phenomenon with many consequences in genetic analysis and population genetics. Epigenetics and complex traits, Springer. 265-285.
  46. Labbe, A. (2013). De la statistique à la génétique, en passant par les mathématiques: identifier les gènes responsables de maladies complexes. Bulletin AMQ, Vol. LIII, no 2.
  47. Labbe, A. and Joober, R. (2013). Response to the letter “Actigraphic evaluation for patients with attention deficit/hyperactivity disorder”. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 162(3), 293.
  48. Huang, O., Labbe, A. and Infante-Rivard, C. (2013). Transmission ratio distortion: review of concept and implications for genetic association studies. [joint first-author]. Human Genetics, 132(3), 245-263.
  49. Labbe, A., Liu, A., Atherton, J., Gizenko, N., Sengupta, S. and Joober, R. (2012) Refining psychiatric phenotypes for response to treatment: contribution of LPHN3 in ADHD.American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 159B(7), 776-785.
  50. Scott-Boyer, M.P., Imholte, G., Tayeb, A., Labbe, A., Deschepper, C. and Gottardo, R. (2012). An integrated hierarchical Bayesian model for multivariate eQTL mapping. Statistical Applications in Genetics and Molecular Biology, 11(4), Article 4.
  51. Labbe, A., Bureau, A., Moreau, I., Roy, M.A., Chagnon, Y., Maziade, M. and Merette, C. (2012) Symptom dimensions as alternative phenotypes to address genetic heterogeneity in schizophrenia and bipolar disorder. European Journal of Human Genetics, 20(11), 1182-1188.
  52. Guevara, D., Champigny, M.D., Tattersall, A., Dedrick, J., Wong, C., Li, Y., Labbe, A., Ping, C., Wang, Y., Nuin, P., Golding, B., McCarry, B., Summers, P.,  Moffatt, B. and Weretilnyk, E. (2012). Transcriptomic and metabolomic analysis of Yukon Thellungiella plants grown in cabinets and their natural habitat show phenotypic plasticity. BMC Plant Biology, 12(175).
  53. Labbe, A. and Dudoit, S. (2012). Special issue on Computational Statistical Methods for genomics and System Biology (editors). Statistical Application in Genetics and Molecular Biology, 11(2).
  54. Oualkacha, K., Labbe, A. , Ciampi, A., Roy, M.A. and Maziade, M. (2012). Principal components of heritability for high dimension quantitative traits and general pedigrees. Statistical Application in Genetics and Molecular Biology, 11(2), Article 4.
  55. Mamdani, F., Berlim, M., Beaulieu, M.M., Labbe, A. , Mérette, C. and Turecki, G. (2011). Gene Expression Biomarkers of Response to Citalopram Treatment in Major Depressive Disorder. Translational Psychiatry, 1(6), e13.
  56. Tayeb, A., Labbe, A. , Bureau, A. and Merette, C. (2011). Solving genetic heterogeneity in extended families by identifying subtypes of complex diseases. Computational Statistics, 26 (3), 539-560.
  57. Bureau, A., Croteau, J., Merette, C. and Labbe, A. (2011). Latent class model with familial dependence to address heterogeneity in complex diseases: adapting the approach to family-based studies. Genetic Epidemiology, 35 (3), 182-189.
  58. Fiori, L., Bureau, A., Labbe, A. , Croteau, J., No‘el, S., Mérette, C., and Turecki, G. (2011). Global Gene Expression Profiling of the Polyamine System in Suicide Completers. The International Journal of Neuropsychopharmacology, 14 (5), 595-605.
  59. Manges, A., Labbe, A. , Atherton, J., Behr, M., Masson, L., Loo, V., Tellis, P. and Brousseau, R. (2010). Comparative metagenomic study of alterations to the intestinal microbiota and risk of nosocomial Clostridum difficile-associated disease. Journal of Infectious Diseases, 202 (12), 1877-1884.
  60. Djebbari, A. and Labbe, A. (2009). Refining gene signatures: a Bayesian approach. BMC Bioinformatics, 10:410.
  61. Labbe, A. , Bureau, A. and Merette, C (2009). Integration of genetic familial structure in latent class models. The International Journal of Biostatistics, 5 (1), Article 6.
  62. Merette, C., Jomphe, V., Labbe, A., Chagnon, Y., Roy, M. A., and Maziade, M. (2009). An Association Study of Candidate Regions that Emerged from Linkage Analyses with Schizophrenia: an Efficient Approach to Control for Multiple Testing and Investigate Interactions. Genetic Epidemiology, 33(8), 826-827.
  63. Vallee, M., Dufort, I., Desrosiers, S., Labbe, A. , Gravel, C., Gilbert, I., Robert C. and Sirard, M.A. (2009). Revealing the bovine embryo transcripts profile during in vivo early embryonic development. Reproduction, 138(1), 95-105.
  64. Gilbert, I., Scantland, S., Dufort, I., Gordynska, O., Labbe, A. , Sirard, M.A., Robert, C. (2009). Real-time monitoring of aRNA production during the T7 amplification increases the discovery potential of microarrays. Nucleic Acids Research, 37(8): e65.
  65. Whiteley, A.R., Derome, N, Rogers , S.M., St-Cyr, J., Laroche, J, Labbe A. , Nolte, A., Renault, S. and Bernatchez, L. (2008) The phenomics of brain transcriptomes regulating adaptive divergence in lake whitefish species pairs from eQTL mapping. Genetics, 180(1), 147-164.
  66. Bureau A., Labbe, A., Croteau, J. and Merette C. (2008). Using disease symptoms to improve detection of linkage under genetic heterogeneity. Genetic Epidemiology, 32(5), 476-486.
  67. Derome, N. Bougas, B., Rogers S., Whiteley, A., Labbe, A. , Laroche, J. and Bernatchez, L. (2008). Pervasive Sex-linked Effects on Transcription Regulation as Revealed by eQTLmapping in Lake Whitefish Species Pairs (Coregonus sp, Salmonidae). Genetics, 179, 1903-1917.
  68. Labbe, A. , Mc Clintick, J. and Martinez M. (2007). Processing/normalization of expression traits. Genetic Epidemiology, 32(5), 476-486.
  69. Labbe, A. , Roth M.P., Carmichael P.H. and Martinez M. (2007). Impact of gene expression data pre-processing on eQTL mapping. BMC proceedings, 1 (Suppl 1): S153.
  70. Miranda Moreno L.F., Labbe, A. and Fu, L. (2007). Bayesian multiple testing procedures for hotspot identification. Accidents Analysis and Preventions, 39(6), 1192-1201.
  71. Labbe, A. and Thompson, M. (2007). Multiple testing using the posterior probabilities of directional alternative: application to genomic studies. The Canadian Journal of Statistics, 35 (1), 51-68.
  72. Wong, C.E., Li, Y., Labbe, A. , Nuin, P., Diaz-Camino, C., Whitty, B., Guevara, D., Golding, G.B., Weretilnyk, E.A., Griffith, M. and Moffatt, B.A. (2005). Transcriptional profiling implicates novel interactions between abiotic stress and hormonal response in Thellungiella, a close relative of Arabidopsis. Plant Physiology, 140, 1437-1450.
  73. Labbe, A. and Thompson, M. (2005). Hierarchical inverse Gaussian models and multiple testing: application to gene expression data. Statistical Applications in Genetics and Molecular Biology, 4 (1).
  74. Miranda Moreno, L.F., Fu, L., Saccomano, F. and Labbe, A. (2005). Alternative risk models for ranking locations for safety improvement. Transportation Research Record, 1908, 1-8.
  75. Labbe, A. and Wormald, H. (2005). On normality, ethnicity, and missing values in quantitative trait locus mapping. BMC Genetics, 6 (Suppl. 1): S52.